WebPascale Delangle *a and Elisabeth Mintz *b Author affiliations Abstract Wilson's disease is an orphan disease due to copper homeostasis dysfunction. Mutations of the ATP7B gene induces an impaired functioning of a Cu-ATPase, impaired Cu detoxification in the liver and copper overload in the body. WebMay 5, 2024 · Copper chelation is the most commonly used therapeutic strategy nowadays to treat Wilson's disease, a genetic disorder primarily inducing a pathological accumulation of Cu in the liver. The mechanism of action of Chel2, a liver-targeting Cu(i) chelator known to promote intracellular Cu chelation, was studied

A Simple Fluorescence Affinity Assay to Decipher …

WebPascale Delangle is on Facebook. Join Facebook to connect with Pascale Delangle and others you may know. Facebook gives people the power to share and makes the world … WebJan 19, 2011 · As expected, P (3) becomes an efficient Cu (I) chelator in the presence of glutathione that mimics the intracellular reducing environment. Finally, cellular uptake … trudy hughes

Relating Structural and Thermodynamic Effects of the Pb(II

WebPascale Delangle Profiles Facebook View the profiles of people named Pascale Delangle. Join Facebook to connect with Pascale Delangle and others you may know. … WebLa plateforme nouvelle génération qui permet à tous les coureurs quel que soit leur niveau, de (re)découvrir le territoire et le patrimoine français, en trouvant les courses qui leur correspondent. WebMay 26, 2024 · @article{Marchioni2024ThiolateCappedSN, title={Thiolate-Capped Silver Nanoparticles: Discerning Direct Grafting from Sulfidation at the Metal–Ligand Interface by Interrogating the Sulfur Atom}, author={Marianne Marchioni and Chiara Battocchio and Yves Joly and Christelle Gateau and Silvia Nappini and Igor P{\'i}{\vs} and Pascale Delangle … trudy howard obituary