Oncostatin m antibody
Web03. apr 2024. · Choy, E.H. et al. Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti- oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo ... WebAbout this Antibody: Name Recombinant Human OSM, 195a.a. (Recombinant Human Oncostatin-M, 195a.a.; rHuOSM, 195a.a.);重组人肿瘤抑制素M,195a.a. Synonyms MGC20461; oncostatin M; oncostatin-M ... Oncostatin M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is …
Oncostatin m antibody
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Web12. apr 2024. · The macrophage oncostatin M (OSM) regulatory pathway was specifically turned on by ischemia. ... In addition, OSM neutralizing antibody significantly reduced OSM expression in macrophages and OSM receptor expression in ischemic tissues (fig. S8, C and D). Compared with the anti–immunoglobulin G (IgG) isotype control group, ... WebThe oncostatin M (OSM) receptor (OSMR) shows frequent gene copy number gains and overexpression in cervical squamous cell carcinomas (SCCs), associated with …
WebOncostatin M induces eotaxin expression in murine lung fibroblasts and is capable of regulating eosinophilic inflammation in an in vivo model, supporting a role for OSM in … WebOncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation.
WebGeneral notes. ab242851 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human Oncostatin M. The recommended pair for sandwich ELISA is: Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. WebMouse Oncostatin M/OSM Antibody Summary. Detects mouse OSM in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react …
WebThe Antibody Pair can be used to quantify Human Oncostatin M. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method.
WebAims: The oncostatin M (OSM) pathway drives fibrosis, inflammation and vasculopathy, and is a potential therapeutic target for inflammatory and fibrotic … roanoke slip and fall lawyerWebOncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. snipes stores near meWebOncostatin M Antibodies Antibodies that detect Oncostatin M can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Neutralization. These antibodies target Oncostatin M in … snipes sneakers philadelphiaWeb05. jan 2015. · Here we describe a chemical biology approach for elucidating potential toxicity mechanisms for thrombosis-related side effects. This work takes advantage of a large chemical biology data set comprising the effects of known, well-characterized reference agents on the cell surface levels of tissue factor (TF) in a primary human … snipes pitch and puttWebMouse Oncostatin M/OSM Antibody Summary Species Reactivity Mouse Specificity Detects mouse OSM in direct ELISAs and Western blots. In direct ELISAs, less than 2% … snipes western hills plazaWebDescription. Oncostatin M antibody LS-C662024 is an unconjugated rabbit monoclonal antibody to Oncostatin M (OSM) from mouse. It is reactive with mouse and rat. Validated for ELISA and WB. snipe the boats spyroWebObjectives: The cytokine oncostatin M (OSM) is implicated in the pathology of systemic sclerosis (SSc). Inhibiting OSM signalling using GSK2330811 (an anti-OSM monoclonal antibody) in patients with SSc has the potential to slow or stop the disease process. roanoke shooting range